Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage

Mayur Doke, Silvia Álvarez-Cubela, Dagmar Klein, Isabella Altilio, Joseph Schulz, Luciana Mateus Gonçalves, Joana Almaça, Christopher A Fraker, Alberto Pugliese, Camillo Ricordi, Mirza Muhammad Fahd Qadir, Ricardo L Pastori, Juan Domínguez-Bendala

Cell Metabolism, vol. 35(11), 2023 Nov

Pericyte dysfunction and impaired vasomotion are hallmarks of islets during the pathogenesis of type 1 diabetes

Luciana Mateus Gonçalves, Mirza Muhammad Fahd Qadir, Maria Boulina, Madina Makhmutova, Elizabeth Pereira, Joana Almaça

Cell Reports, vol. 42(8), 2023 Aug

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

GBD Collaborators

The Lancet, 2023 Jun

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

Weiwei Xu, Fahd Qadir, Daniela Nasteska, Paula Mota de Sá, C. Gorvin, M. Blandino-Rosano, Charles R. Evans, Thuong Ho, E. Potapenko, R. Veluthakal, F. Ashford, S. Bitsi, Jia Fan, Manika Bhondeley, K. Song, Venkata N Sure, Siva S. V. P. Sakamuri, L. Schiffer, W. Beatty, R. Wyatt, D. Frigo, Xiaowen Liu, P. Katakam, W. Arlt, J. Buck, L. Levin, Tony Y. Hu, J. Kolls, C. Burant, Alejandra Tomas, M. Merrins, D. Thurmond, E. Bernal-Mizrachi, D. Hodson, F. Mauvais-Jarvis

Cell Reports, 2023 May

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

GBD Collaborators

The Lancet, 2022

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

GBD Collaborators

Lancet. Infectious Diseases (Print), 2022

Efficacy of glucagon-like peptide-1 and estrogen dual agonist in pancreatic islets protection and pre-clinical models of insulin-deficient diabetes

Taylor T Fuselier, Paula Mota de Sá, Fahd Qadir, Beibei Xu, C. Allard, Matt Meyers, J. Tiano, Bin Yang, V. Gelfanov, S. Lindsey, R. DiMarchi, F. Mauvais-Jarvis

Cell Reports Medicine, 2022

SARS-CoV-2 infection of the pancreas promotes thrombofibrosis and is associated with new-onset diabetes

Fahd Qadir, Manika Bhondeley, W. Beatty, D. Gaupp, L. Doyle-Meyers, T. Fischer, I. Bandyopadhyay, R. Blair, R. Bohm, J. Rappaport, E. Lazartigues, R. V. Vander Heide, J. Kolls, X. Qin, F. Mauvais-Jarvis

JCI insight, 2021

The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

GBD Collaborators

The Lancet. Oncology, 2021

Endothelial c‐Myc knockout enhances diet‐induced liver inflammation and fibrosis

Y. Qi, Fahd Qadir, A. Hastreiter, R. Fock, J. F. Machi, A. Morales, Ying Wang, Z. Meng, Claudia O Rodrigues

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021

Endocrine Significance of SARS-CoV-2’s Reliance on ACE2

E. Lazartigues, Fahd Qadir, F. Mauvais-Jarvis

Endocrinology, 2020

Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche

Fahd Qadir, Silvia Álvarez-Cubela, D. Klein, Jasmijn van Dijk, Rocío Muñiz-Anquela, Yaisa B Moreno-Hernández, G. Lanzoni, Saad Sadiq, Belén Navarro-Rubio, Michael T. Garcia, Á. Díaz, Kevin Johnson, David W Sant, C. Ricordi, A. Griswold, R. Pastori, J. Domínguez-Bendala

Proceedings of the National Academy of Sciences, 2020

Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Fahd Qadir, Silvia Álvarez-Cubela, Jonathan R. Weitz, J. Panzer, D. Klein, Yaisa B Moreno-Hernández, S. Cechin, Alejandro Tamayo, Joana Almaça, H. Hiller, M. Beery, I. Kusmartseva, M. Atkinson, S. Speier, C. Ricordi, A. Pugliese, A. Caicedo, C. Fraker, R. Pastori, J. Domínguez-Bendala

Nature Communications, 2020

Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis.

J. Panzer, H. Hiller, C. Cohrs, Joana Almaça, Stephen J. Enos, M. Beery, S. Cechin, D. M. Drotar, Jonathan R. Weitz, Jorge Santini, Mollie K. Huber, Mirza Muhammad Fahd Qadir, R. Pastori, J. Domínguez-Bendala, E. A. Phelps, M. Atkinson, A. Pugliese, A. Caicedo, I. Kusmartseva, S. Speier

JCI insight, 2020

Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion

Weiwei Xu, L. Schiffer, Fahd Qadir, Yanqing Zhang, J. Hawley, Paula Mota de Sá, B. Keevil, Hongju Wu, W. Arlt, F. Mauvais-Jarvis

Diabetes, 2020

Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signaling

Jonathan R. Weitz, Carol Jacques-Silva, Fahd Qadir, O. Umland, E. Pereira, Farhan Qureshi, Alejandro Tamayo, J. Domínguez-Bendala, R. Rodriguez-Diaz, Joana Almaça, A. Caicedo

Diabetes, 2020 Jun

A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Fahd Qadir, Silvia Álvarez-Cubela, Kinsley C. Belle, T. Sapir, F. Messaggio, Kevin Johnson, O. Umland, Darrell Hardin, D. Klein, I. Pérez-Álvarez, Fatima Sadiq, O. Alcázar, L. Inverardi, C. Ricordi, P. Buchwald, C. Fraker, R. Pastori, J. Domínguez-Bendala

Stem cell reports, 2019

Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice

Fahd Qadir, A. Bhatti, M. Ashraf, M. A. Sandhu, Sidrah Anjum, P. John

Inflammopharmacology, 2018

P2RY1/ALK3-Expressing Cells within the Adult Human Exocrine Pancreas Are BMP-7 Expandable and Exhibit Progenitor-like Characteristics

Fahd Qadir, Silvia Álvarez-Cubela, D. Klein, G. Lanzoni, Carlos A. Garcia-Santana, A. Montalvo, Fabiola PlÁceres-Uray, E. Mazza, C. Ricordi, L. Inverardi, R. Pastori, J. Domínguez-Bendala

Cell reports, 2018

Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients.

Fahd Qadir, A. Bhatti, Rabia Khurshid, M. Ashraf, Sidrah Anjum, P. John

Pakistan journal of pharmaceutical sciences, 2016

Emerging diabetes therapies: Bringing back the β-cells

G. Basile, Fahd Qadir, F. Mauvais-Jarvis, A. Vetere, V. Shoba, A. E. Modell, R. Pastori, H. A. Russ, B. Wagner, J. Domínguez-Bendala

Molecular metabolism, 2022

Temporal single-cell regeneration studies: the greatest thing since sliced pancreas?

J. Domínguez-Bendala, Fahd Qadir, R. Pastori

Trends in Endocrinology & Metabolism, 2021

The Role of MicroRNAs in Diabetes-Related Oxidative Stress

Fahd Qadir, D. Klein, Silvia Álvarez-Cubela, J. Domínguez-Bendala, R. Pastori

International journal of molecular sciences, 2019

Pancreatic Progenitors: There and Back Again

J. Domínguez-Bendala, Fahd Qadir, R. Pastori

Trends in Endocrinology & Metabolism, 2019

Animal cloning applications and issues

F. Ibtisham, M. M. Fahd Qadir, M. Xiao, L. An

Russian Journal of Genetics, 2017

RANKL Signaling Pathway: A Potential Target for Antiresorptive Therapy in Rheumatoid Arthritis

Sidrah Anjum, A. Bhatti, Fahd Qadir, Usman Ashraf, P. John

NJNS, 2015

MicroRNAs in Pancreas and Islet Development and Function

Juan Domínguez-Bendala, Dagmar Klein, Mirza Muhammed Fahd Qadir, Ricardo L Pastori

MicroRNA in Regenerative Medicine, chapter 12, 2nd ed., Academic Press, 2023 Jan

Human pancreatic progenitors

Fahd Qadir, G. Lanzoni, C. Ricordi, J. Domínguez-Bendala

2nd, Academic Press, 2020

Development of Bioartificial Pancreas/Pancreas Organoids

Fahd Qadir, Silvia Álvarez-Cubela, M. Bellio, D. Klein, R. Pastori, J. Domínguez-Bendala

Reference Module in Biomedical Sciences, 2019

The Adverse Impact of Modern Biotechnology on the Environment

Fahd Qadir, A. Bhatti, P. John

Springer, 2015